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U.S. Nucleic Acid Isolation and Purification Markets

DateSep, 2003
Pages0
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Abstract:

Resistance by Purists Blocks Adoption of Nucleic Acid Isolation Solutions

Researchers trained before the introduction of DNA and RNA isolation kits will be the hardest to convince about the benefits of nucleic acid separation products. These researchers, who form a significant segment of the research community, resist changes to the traditional isolation processes fearing that any alteration in variables will affect the results. Paltry research budgets further increase their resistance to the new technology. Manufacturers can work around these apprehensions by promoting the significant cost advantages of the kits as well as designing special packages for niche applications. Positive customer experience can lead to product loyalty, which in turn, can increase sales of these consumables that have started to be commoditized.

This research examines the U.S. nucleic acid isolation markets. It provides key market drivers, restraints affecting growth, and offers recommendations to overcome market challenges. The research has been divided into two segments: consumables and instrumentation. The products have been segmented by volume and application.

Low Cost of Commercially Available Products to Wean Users away from Traditional Methods

There is a vast untapped market for commercially available products since 75-80 percent of nucleic acid isolations are conducted using traditional methods such as phenol/chloroform extraction. Home-brew methods lack the quality of commercially available methods and are protracted processes. Moreover, their associated costs of labor, hazardous waste disposal, capital equipment, and instrument maintenance are prohibitive. Manufacturers of commercially available products have to play up the cost advantage of their kits through marketing campaigns.

Effective cost management is critical for successful research programs in both academia and the private sector. Customers have indicated that their purchase decisions are influenced by reviews and comparative analysis of products in the media. Enterprises competing in the commercial nucleic acid isolation market have to invest in product review websites or contribute to trade publication, states the analyst. Manufacturers can also facilitate purchase and adoption by offering auxiliary consumables at a discount for companies that purchase their core products.

New Technologies and Applications Expand Customer Base

The development of the molecular diagnostics market, coupled with a growing number of sequencing and functional genomic initiatives have contributed to substantial expansion of the marketplace, notes the analyst. Techniques such as cloning and peak cell rate amplification have moved out of the confines of genetics laboratories and have started being used as common research tools.

Manufacturers have started to introduce microarrays that can analyze sequence variations in genes involved in drug metabolism to determine the best treatment regime. Moreover, diagnostic techniques of proven utility in disease management such as genotyping and viral load monitoring have begun to be applied in nucleic acid isolation and purification products. These emerging technologies and expanded applications of existing technologies are expected to enlarge the user base for nucleic acid isolation processes.










Table of contents:
 1. Executive Summary
      1. Executive Summary

2. Total Market
      1. Market Overview
           1. Introduction
           2. Selected Market Players
           3. Significant Market Events
           4. Research Methodology
      2. Market Segmentation and Revenue Forecast
           1. Market Segmentation
           2. Revenue Forecast
      3. Challenges and Strategies
           1. Market Challenges
               a. Cost of Instrumentation Prohibits Adoption and Hinders Market
               b. Slowed Growth of R&D Spending Limits Growth of Market
               c. Growing View of DNA/RNA Isolation Products as a Commodity
                   Limits Growth
               d. Shrinking Number of Customers Limits Market Potential for Some
                   Manufacturers
               e. Growing Number of Sample Types Increases Need for Specialized Products
               f. Trends in Processing Volume Negatively Effect Some Manufacturers
               g. Resistance by Research Community Limits Adoption of Nucleic Acid
                   Isolation Products
           2. Strategic Recommendations
               a. Develop Marketing Campaigns that Highlight Cost Benefit of Using
                   Commercially Available Products
               b. Focus Efforts on the Establishment of Market-Leading Products
                   for Niche Applications
               c. Establish and Promote Financing and Incentive Programs that
                   Allow for Increased Adoption and Purchase of Instrumentation
               d. Focus Development and Marketing Efforts Towards Healthcare
                   Sample Preparations Market

- - - e. Value Focused Products Lead to Increased Adoption and Sales Volume

3. Consumables
      1. Market Overview
           1. Introduction
           2. Market Drivers
               a. Growth of Molecular Diagnostics Market Drives Sales for Nucleic
                   Acid Isolation Products
               b. Growing Use of High Throughput Nucleic Acid Isolation Products
                   Drives Market
               c. Growing Employment of Microarrays Drives Sales of Nucleic Acid
                   Isolation Products
               d. Sequencing of Human Genome Spurs Use of Nucleic Acid Based Technologies
               e. Necessity for Highly Reproducible Nucleic Acid Isolations Contributes
                   Positively to Market Growth
               f. Variety of Specialized Kits Cultivates Market Growth
               g. Cost of Waste and Time from Traditional Methods Drives Adoption of
                   Nucleic Acid Isolation Kits
           3. Market Restraints
               a. View of Products as a Commodity Limits Revenue Growth
               b. Use of Oligonucleotides for Probes and Microarray Construction Restricts
                   Market
               c. New Technologies Require Less Sample Processing and Limits Market
                   for Nucleic Acid Isolation Products
               d. Popularity of Traditional Methods Continues to Restrain Market for Nucleic
                   Acid Isolation Products
               e. Downstream Research (Such as Proteomics) Creates Competition for
                   Finite Research Dollars
           4. Market Engineering Analysis
      2. Revenue Forecast and Market Trends
           1. Revenue Forecast
           2. Demand Analysis
           3. Market and Technology Trends
      3. Competitive Analysis
           1. Competitive Structure
           2. Market Share Analysis
           3. Product Analysis

4. Instrumentation
      1. Market Overview
           1. Introduction
           2. Market Drivers
               a. Growth of Molecular Diagnostic Testing Spurs Sales
               b. Need for Increased Sequencing Capacity Drives Market for High
                   Throughput Instrumentation
               c. Medical Community’s Growing Dependence on Commercial Laboratories
                   Promotes Market Growth
               d. Focus On High Throughput Functional Genomics Stimulates Market for
                   Instrumentation Products
           3. Market Restraints
               a. Trends in Government Funding Negatively Affects the Majority of
                   Sequencing Centers and Hinders Market
               b. High Cost of Instrumentation is Prohibitive for Many Laboratories and
                   Curbs Purchase
               c. Number of Companies Offering Isolation Instrumentation Increases
                   Competition and Reduces Market Potential
               d. Growth of Core Lab Initiatives Reduces Potential Number of Customers
                   and Curbs Market
           4. Market Engineering Analysis
      2. Revenue Forecast and Market Trends
           1. Revenue Forecast
           2. Demand Analysis
           3. Market and Technology Trends
      3. Competitive Analysis
           1. Competitive Structure
           2. Market Share Analysis
           3. Product Analysis

5. End-User Study and Frost & Sullivan Awards
      1. End-User Study
           1. End-User Study
      2. Frost & Sullivan Awards
           1. Overall Product Quality Leadership
           2. Overall Product Innovation
           3. RNA Product Quality
           4. DNA Product Quality
           5. Instrumentation Product Quality
           6. Consumables Customer Service Leadership
          7. Instrumentation Customer Service Leadership

6. Decision Support Database
      1. Decision Support Database
           1. Sequencing Initiatives
           2. Sequencing Centers
           3. Research Universities
           4. Biological and Medical Scientists
  

List Of Figures

Chapter 2

Nucleic Acid Isolation Market: Selected Significant Market Events (U.S.), 2002-2003
Nucleic Acid Isolation Market: Total Market Revenue Forecasts (U.S.), 2001-2009
Nucleic Acid Isolation Market: Impact of Top Industry Challenges (U.S.), 2003-2009
Nucleic Acid Isolation Market: Challenges and Corresponding Strategies (U.S.), 2003-2009

Chapter 3

Nucleic Acid Isolation Consumables Market: Market Drivers Ranked in Order of Impact (U.S.), 2003-2009
Nucleic Acid Isolation Consumables Market: Market Restraints Ranked in Order of Impact (U.S.), 2003-2009
Nucleic Acid Isolation Consumables Market: Revenue Forecasts (U.S.), 2001-2009
Nucleic Acid Isolation Consumables Market: Competitive Structure (U.S.), 2002
Nucleic Acid Isolation Consumables Market: Market Share Analysis (U.S.), 2002
Nucleic Acid Isolation Consumables Market: Select Products Offered by Major Market Participants (U.S.), 2002

Chapter 4

Nucleic Acid Isolation Instrumentation Market: Market Drivers Ranked in Order of Impact (U.S.), 2003-2009
Nucleic Acid Isolation Instrumentation Market: Market Restraints Ranked in Order of Impact (U.S.), 2003-2009
Nucleic Acid Isolation Instrumentation Market: Revenue Forecast (U.S.), 2001-2009
Nucleic Acid Isolation Instrument Market: Competitive Structure (U.S.), 2002
Nucleic Acid Isolation Instrumentation Market: Market Share Analysis (U.S.), 2002
Nucleic Acid Isolation Instrumentation Market: Select Products Offered by Major Market Participants (U.S.), 2002




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