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Laboratory Chemical Reagents - Global Strategic Business Report

DateJan, 2006
Pages820
Price / format€3938 / Electronic
€3938 / Hard Copy

€3 938 

Report Information | Custom-Tailored Research | Product Trade Lead


Abstract:
 This report analyzes the worldwide markets for Laboratory Chemical Reagents in Millions of US$. The major product segments analyzed are Molecular Biology, Biochemistry (IVD), Cytokine & Chemokine Testing, Cell/Tissue Culture, Carbohydrate Analysis, Immunohistochemistry, and Environmental Testing. The sub-product segments discussed include Monoclonal & Polyclonal Antibodies, Gene Expression, Vectors, Cloning, & Sequencing, Gene Synthesis, Extraction Kits, PCR Reagents, Enzymes, and Pesticide Residues. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World. Annual forecasts are provided for each region for the period of 2000 through 2010. The report profiles 230 companies including players worldwide such as Amersham Biosciences (ABS), Applied Biosystems, Beckman Coulter, Becton, Dickinson and Company (BD), Biomerieux, Dionex Corp., Merck KGaA, EMD Chemicals, Inc., Owl Separation Systems, PerkinElmer, Shimadzu Scientific Instruments, Sigma-Aldrich Corp., Takara Biomedical Group, Waters Corp., Wako Pure Chemical Industries, Strategic BioSolutions, CALTAG Laboratories, Gallus Immunotech, Lonza Biologics, Maine Biotechnology Services, O.E.M. Concepts, Inc., Gentra Systems, Inc., QIAGEN, A.G. Scientific, Inc., Biosource International, Inc., Kirkegaard & Perry Laboratories, Promega Corporation, R&D Systems, Cytimmune Science, GenHunter Corporation, Qbiogene, Advanced Biotechnologies, Inc., Analytical Biological Services, Inc., Invitrogen Corp., JRH Biosciences, Mediatech, BioMed Labs, Pierce Chemical Co., J.T. Baker, and Strategic Diagnostics.

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Table of contents:
 LABORATORY CHEMICAL REAGENTS
A GLOBAL STRATEGIC BUSINESS REPORT


CONTENTS


I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

II.
1. Market Dynamics II-1
Trends II-1
Biotechnology Reagents and Supplies
Among the Fastest
Growing Markets II-1
Automated Instrumentation
Playing a Major Role II-2
Players Undergo Paradigm Shift II-2
Proteomics
An Emerging Complex Industry II-2
High Growth Applications Spur Industry Growth II-2
Separation Technologies
Highly Competitive II-3
Kits Continue to Gain Popularity II-3

2. Product Overview II-4
A. Molecular Biology II-4
Monoclonal Antibodies II-4
Recombinant Antibodies
Holding Potential II-5
FDA Classification of Monoclonal Antibodies II-5
Types of Monoclonal Antibodies II-5
Applications II-6
Regulatory Status II-7
Polyclonal Antibodies II-7
Gene Expression II-8
DNA: The Basis for Modern Biotechnology II-8
Trends in Gene Expression Market II-8
Technologies Available for Gene Expression Analysis II-9
Gene Vectors, Cloning & Sequencing II-9
DNA Cloning II-10
DNA Sequencing II-10
Kits for DNA Sequencing II-10
Manual Sequencing Vs. Automated II-10
Role of DNA Sequencing II-10
SNP Market Springs Opportunities II-11
Gene Synthesis II-11
Extraction Kits II-11
Demand for Automated Extraction Systems II-12
Research Market for Nucleic Acid Separation and
Purification Products II-12
Major Players II-12
PCR & Other Lab Enzymes II-12
Polymerase Chain Reaction (PCR) II-13
B. Biochemistry II-14
Some of the Major Reagent Compounds Used in Biochemistry II-14
Reagents used in Signal Transduction II-14
Calcium Fluorescent Indicators II-14
pH Fluorescent Indicators and pH Gradient Indicators II-14
Inositols II-14
Reagents Used in Cross-linking II-15
Hetero-Bifunctional Reagents II-15
Homo-Bifunctional Reagents II-15
Reagents Used in Labeling II-15
Reagents Used for Cell Viability and Proliferation Assays II-15
Living Cell Counting II-15
Cell Staining II-16
Reagents Used as Photolabile Compounds/Caged Compounds II-16
Nucleotides II-16
Proton II-16
Calcium II-16
Fluorophores II-16
Reagents Used for Cell Membrane Research II-16
Membrane Probes II-16
Other Types II-17
C. Cytokine & Chemokine Testing II-17
Enzyme-Linked Immunosorbent Assay (ELlSA) II-17
ELISA-based Diagnostics Kits Account for Major Share II-17
BioSignature’s Multiplex ELISA Technology
A Major
Breakthrough II-17
Elements of ELISA II-17
Chemokines II-18
Classification of Chemokines II-18
Role of Chemokines II-18
Cytokines II-19
Changing Definitions II-19
Classification of Cytokines II-19
D. Cell Culture II-20
Cell & Tissue Culture Reagents II-20
Tissue Culture II-20
Trends II-21
Growth in Serum-Free Media II-21
Contract Cell Culture Optimization II-21
E. Immunohistochemistry II-21
Walk Away Instrument Reagents Systems Pose Significant
Opportunity II-22
IHC Staining II-22
F. Carbohydrate Analysis II-22
Customer Base II-22
Glycobiology II-22
Role of Carbohydrates as Recognition Molecules II-23
Enzymes Used in Carbohydrate Analysis II-23
G. Environmental Testing II-24
Kits
Introduction II-24
Use of Precipitating Reagents II-24

3. End Use Industry Analysis II-25
Analysis by End-Use II-25
Academic Segment II-25
Commercial Interests and Issues II-25
National Institutes of Health (NIH) II-25
Non-Academic Segment II-25
Corporate Segment II-25
Biotechnology
A Large and Diverse Industry II-26
Growing Nexus between Biotech and Pharma Companies II-26

4. Distribution Logistics II-27
Distribution Practices II-27
Economics of Razor/Razor Blade Business Model II-27
Beating Prices II-27
Increase in Contract Manufacturing Services II-28
Factors Impacting Growth II-28
Business Models Driving the Need for Contract Manufacturing II-28
Trends in Contract Manufacturing II-28
General Policies and Conditions II-29
Regulatory Guidelines II-29
MSDS and Hazardous Information II-29

5. Product Launches II-30
bioMйrieux Launches CE-IVD Approved Platform II-30
bioMйrieux Launches NucliSens and NucliSens Magnetic
Extraction Reagents II-30
Do-Coop Technologies Launches Water-based Nano-Reagent II-30
Promega Unveils New Rapid Response Reporter Vectors for
Cellular Analysis II-30
New Cell Cycle Assay for Cell Research II-30
Affymetrix Inc, and Invitrogen Launch GeneChip Reagents II-31
U.S. Genomics Launches Direct miRNA Reagents II-31
SPIE-IA for Small Molecule Study II-31
Reagents for Cell-Free Protein Synthesis II-31
Invitrogen Launches cDNA Library Construction Kit II-31
PharmaDesign Develops New Regents II-32
Invitrogen Launches OligofectAMINE Reagent II-32
Tecan Systems Introduces DNA Extraction Kits II-32
XTRANA Rolls Out Genomic DNA Extraction Kit II-32
New Invader Clinical Reagents for Clinical Use II-32
Proligo Introduces TrueSNP Primer Kit II-32
Minerva Biolabs Launches Reagents and Diagnostic Kits II-33
Link Launches Reagent Kit II-33
ABG Unveils TaqMan GMO Detection and Quantitation Kit II-33
Argonaut Introduces Organic Synthesis and Purification
Accelerating Reagents II-33
AB Launches New Range of Plusone Clean-Up Kits and Reagents II-33
DYEnamic ET terminator DNA Sequencing Kit for Capillary
Sequencing II-34
Amersham Biosciences Launches Reagent Kit II-34
ABI Unveils New Elisa Test Kit II-34
Invitrogen Launches Directional TOPO Entry Vector II-34
Qiagen Inc Releases ProofStart DNA Polymerase II-34
Beckman Coulter Unveils Ready-to-Use Histocompatibility
Complex Tetramer Reagents II-35
Molecular Devices Corp Launches Reagent Kits II-35
Life Science Kits for Genomic Applications II-35
Prolinx Inc Unveils Proteomics Products II-35
Invitrogen Reveals Advanced Granulation Technology (AGT) II-35
Trevigen Introduces Antibodies, Kits & Reagents II-36
Argonaut Technologies Launches Three Reagents II-36

6. Recent Industry Activity II-37
Serologicals Strengthens Market Position in Cell Research
Segment II-37
Eterna Zentaris Acquires Echelon Biosciences II-37
Galapagos Acquires BioFocus II-37
eGene Forms Alliance with Transgenomic II-37
Takara Bio Takes Over Clontech Unit of BD Biosciences II-37
Invitrogen Acquires Dynal Biotech II-38
Biotage Acquires American Argonaut Technologies II-38
Invitrogen Acquires Antibody Manufacturer II-38
Chemicon Signs Agreement with Quantum Dot II-38
Dharmacon Pens Agreement with Genentech II-39
Lynx and Solexa Merge to Form Solexa II-39
Genetics Receives Market Exclusivity for Cancer Genetics
Diagnostic Probe Reagents II-39
Clinical Data Obtains Distribution Rights for Melet’s
Hematology Reagents II-39
Sigma- Aldrich Owns JRH Biosciences II-39
Meridian Acquires O.E.M. Concepts II-40
Bio-Rad Acquires MJ GeneWorks II-40
Invitrogen Acquires Bio Asia II-40
IDEXX Purchases Bommeli Diagnostics II-40
GE Acquires Amersham Plc II-40
CalbaTech Acquires K-D Medical II-41
Chemicon to Market Thromb’s Stem Cell Reagents II-41
Tepnel Acquires Diaclone II-41
Leica Enters into Alliance with Sigma for Histology and
Cytology Stains and Reagents II-41
Agilent Creates New Life Sciences Unit II-41
D. Lansing Taylor Join Forces with PLSG to Create Cellumen II-42
Cell Signaling Technology and Zeptosens AG Sign Licensing
Agreement for CST reagents II-42
Cell Signaling Technology, Signs Agreement with ProQinase GmbH II-42
Cosmo Bio Establishes New US Subsidiary II-42
2000-2003 Archive II-42

7. Focus on Major Players & Suppliers II-47
Amersham Biosciences (ABS) (US) II-47
Applied Biosystems (US) II-47
Beckman Coulter (US) II-48
Becton, Dickinson and Company (BD) (US) II-48
Biomerieux (France) II-48
Dionex Corp (US) II-49
Merck KGaA (Germany) II-49
EMD Chemicals Inc II-49
Owl Separation Systems(US) II-49
PerkinElmer(US) II-50
Shimadzu Scientific Instruments (Japan) II-50
Sigma-Aldrich Corp. II-50
Takara Biomedical Group (Japan) II-50
Waters Corp (US) II-51
Wako Pure Chemical Industries (Japan) II-51
Monoclonal and Polyclonal Antibodies Suppliers II-52
Strategic BioSolutions (US) II-52
CALTAG Laboratories (US) II-52
Gallus Immunotech (US) II-52
Lonza Biologics (Switzerland) II-52
Maine Biotechnology Services (US) II-52
O.E.M. Concepts, Inc. (US) II-53
Nucleic Acid Extraction Kits Suppliers II-53
Gentra Systems, Inc. (US) II-53
QIAGEN(US) II-53
Biochemistry Reagents and Related Chemical SuppliersII-53 A.G.
Scientific, Inc (US) II-53
Biosource International, Inc (US) II-53
Kirkegaard & Perry Laboratories (US) II-54
Promega Corporation (US) II-54
Cytokine and Chemokine Testing Reagent and Kits Suppliers II-54
R&D Systems (US) II-54
Cytimmune Science (US) II-54
Differential Display kits Suppliers II-54
GenHunter Corporation (US) II-54
Qbiogene (US) II-55
Cell Culture Suppliers II-55
Advanced Biotechnologies Inc. (US) II-55
Analytical Biological Services Inc II-55
Invitrogen Corp. (US) II-55
JRH Biosciences (US) II-55
Mediatech (US) II-56
Carbohydrate Analysis Reagents Suppliers II-56
BioMed Labs (UK) II-56
Pierce Chemical Co(US) II-56
Environmental Testing Reagents Suppliers II-56
J.T. Baker (US) II-56
Strategic Diagnostics (US) II-57

8. Global Market Perspective II-58
Table 1: World Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-58

Table 2: World 10-Year Perspective for Laboratory Chemical
Reagents by Geographic Region
Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia- Pacific (excluding
Japan), Latin America and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-58

Table 3: World Recent Past, Current & Future Analysis for
Molecular Biology Reagents by Geographic Region
US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2000 through 2010
(includes corresponding Graph/Chart) II-59

Table 4: World Recent Past, Current & Future Analysis for
Molecular Biology Reagents by Product Segment
Monoclonal &
Polyclonal Antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction Kits, PCR Reagents,
Enzymes, and Others Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-59

Table 5: World 10-Year Perspective for Molecular Biology
Reagents by Geographic Region
Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-60

Table 6: World 10-Year Perspective for Molecular Biology
Reagents by Product Segment
Percentage Breakdown of Dollar
Sales for Monoclonal & Polyclonal Antibodies, Gene Expression,
Vectors, Cloning, & Sequencing, Gene Synthesis, Extraction
Kits, PCR Reagents, Enzymes, and Others Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-60

Table 7: World Recent Past, Current & Future Analysis for
Monoclonal & Polyclonal Antibodies Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-61

Table 8: World 10-Year Perspective for Monoclonal & Polyclonal
Antibodies by Geographic Region
Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets for
Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-61

Table 9: World Recent Past, Current & Future Analysis for Gene
Expression, Vectors, Cloning, & Sequencing Reagents by
Geographic Region
US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2000 through 2010 (includes corresponding
Graph/Chart) II-62

Table 10: World 10-Year Perspective for Gene Expression,
Vectors, Cloning, & Sequencing Reagents by Geographic Region -
Percentage Breakdown of Dollar Sales for US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Latin America and Rest
of World Markets for Years 2000, 2005 & 2010 (includes
corresponding Graph/Chart) II-62

Table 11: World Recent Past, Current & Future Analysis for
Gene Synthesis Reagents by Geographic Region
US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2000 through 2010
(includes corresponding Graph/Chart) II-63

Table 12: World 10-Year Perspective for Gene Synthesis
Reagents by Geographic Region
Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia- Pacific
(excluding Japan), Latin America and Rest of World Markets for
Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-63

Table 13: World Recent Past, Current & Future Analysis for
Extraction Kits by Geographic Region
US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Latin America and Rest
of World Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) II-64

Table 14: World 10-Year Perspective for Extraction Kits by
Geographic Region
Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America and Rest of World Markets for Years 2000, 2005 &
2010 (includes corresponding Graph/Chart) II-64

Table 15: World Recent Past, Current & Future Analysis for PCR
Reagents by Geographic Region
US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Latin America and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) II-65

Table 16: World 10-Year Perspective for PCR Reagents by
Geographic Region
Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America and Rest of World Markets for Years 2000, 2005 &
2010 (includes corresponding Graph/Chart) II-65

Table 17: World Recent Past, Current & Future Analysis for
Enzymes by Geographic Region
US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Latin America and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) II-66

Table 18: World 10-Year Perspective for Enzymes by Geographic
Region
Percentage Breakdown of Dollar Sales for US, Canada,
Japan, Europe, Asia- Pacific (excluding Japan), Latin America
and Rest of World Markets for Years 2000, 2005 & 2010
(includes corresponding Graph/Chart) II-66

Table 19: World Recent Past, Current & Future Analysis for
Other Molecular Biology Reagents by Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-67

Table 20: World 10-Year Perspective for Other Molecular
Biology Reagents by Geographic Region
Percentage Breakdown
of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets for
Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-67

Table 21: World Recent Past, Current & Future Analysis for
Reagents Used in Biochemistry by Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-68

Table 22: World 10-Year Perspective for Reagents Used in
Biochemistry by Geographic Region
Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets for
Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-68

Table 23: World Recent Past, Current & Future Analysis for
Cytokine & Chemokine Testing Reagents by Geographic Region -
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America and Rest of World Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2000
through 2010 (includes corresponding Graph/Chart) II-69

Table 24: World 10-Year Perspective for Cytokine & Chemokine
Testing Reagents by Geographic Region
Percentage Breakdown
of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets for
Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-69

Table 25: World Recent Past, Current & Future Analysis for
Reagents Used in Cell Culture by Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-70

Table 26: World 10-Year Perspective for Reagents Used in Cell
Culture by Geographic Region
Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-70

Table 27: World Recent Past, Current & Future Analysis for
Reagents Used in Carbohydrate Analysis by Geographic Region -
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America and Rest of World Markets Independently analyzed
with Annual Sales Figures in US$ Million for Years 2000
through 2010 (includes corresponding Graph/Chart) II-71

Table 28: World 10-Year Perspective for Reagents Used in
Carbohydrate Analysis by Geographic Region
Percentage
Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia
-Pacific (excluding Japan), Latin America and Rest of World
Markets for Years 2000, 2005 & 2010 (includes corresponding
Graph/Chart) II-71

Table 29: World Recent Past, Current & Future Analysis for
Immunohistochemistry Reagents by Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-72

Table 30: World 10-Year Perspective for Immunohistochemistry
Reagents by Geographic Region
Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia- Pacific (excluding
Japan), Latin America and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-72

Table 31: World Recent Past, Current & Future Analysis for
Reagents Used in Environmental Testing by Geographic Region -
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America and Rest of World Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2000
through 2010 (includes corresponding Graph/Chart) II-73

Table 32: World Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Product Segment
Pesticide
Residues and Other Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2000 through 2010
(includes corresponding Graph/Chart) II-73

Table 33: World 10-Year Perspective for Reagents Used in
Environmental Testing by Geographic Region
Percentage
Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia
-Pacific (excluding Japan), Latin America and Rest of World
Markets for Years 2000, 2005 & 2010 (includes corresponding
Graph/Chart) II-74

Table 34: World 10-Year Perspective for Laboratory Chemical
Reagents by Product Segment
Percentage Breakdown of Dollar
Sales for Pesticide Residue and Other Markets for Years 2000,
2005 & 2010 II-74

Table 35: World Recent Past, Current & Future Analysis for
Pesticide Residues Testing Reagents by Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-75

Table 36: World 10-Year Perspective for Pesticide Residues
Testing Reagents by Geographic Region
Percentage Breakdown
of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets for
Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-75

Table 37: World Recent Past, Current & Future Analysis for
Other Environment Testing Reagents by Geographic Region
US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-76

Table 38: World 10-Year Perspective for Other Environment
Testing Reagents by Geographic Region
Percentage Breakdown
of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets for
Years 2000, 2005 & 2010(includes corresponding Graph/Chart) II-76


III. MARKET

1. The United States III-1
A.Market Analysis III-1
Market for Laboratory Chemical Reagents III-1
Biotechnology Reagents Market Review III-1
Table 39: Laboratory Chemical Reagents Market in the US:
Percentage Breakdown by End Use for Corporate, Academic,
and Non-academic includes corresponding Graph/Chart) III-1

Table 40: US Reagent Kits Market (2004): Percentage
Breakdown by Application for Target Amplification,
Detection Systems, DNA Sequencing kits, Cloning and cDNA
Kits, Single Amplification, and Other Kits (includes
corresponding Graph/Chart) III-1
Production and R&D to Drive US Media, Sera and Reagents Market III-2
Players in the Laboratory Chemical Reagents Market III-2
Leading Specialist Companies By Segment Type III-2
Market Analysis By Segment III-2
Molecular Biology III-2
Table 41: Molecular Biology Research Reagents and Kits
Market in the US: Percentage Breakdown by End Use for
Academic, Biotech, Pharmaceutical, and Government
(includes corresponding Graph/Chart) III-3
Rating of Factors Contributing to Brand Preference for
Monoclonal Antibodies among Researchers (On Scale of 1-5) III-3
Gene Sequencing III-3
PCR & Other Lab Enzymes III-4
Cytokine & Chemokine Testing (Immunoassay) III-4
Table 42: US Laboratory Chemical Reagents Market:
Percentage Breakdown of Organizations Engaged in Use of
Cytokines and Growth Factors for High, Middle, Moderate,
and Novice (includes corresponding Graph/Chart) III-4
Immunoassay Reagents III-5
Immunohistochemistry III-5
Cell & Tissue Culture III-5
Table 43: US Cell Culture Market (2004): Percentage
Breakdown by Segment Usage for Liquid Media, Powdered
Media, Fetal Bovine Serum, Other sera, Growth, Factors,
Cell culture, Supplements, Serum free, Protein-free Media,
and Other products (includes corresponding Graph/Chart) III-6
Environmental Testing III-6
Pesticide Residues III-7
Product Launches III-7
Strategic Corporate Developments III-11
Select Major Players in the US Market for Reagents III-20
Amersham Biosciences/GE HealthCare III-20
Applied Biosystems III-20
Beckman Coulter III-21
Becton Dickinson III-21
Dionex Corp. III-21
EMD Bisociences III-22
Owl Separation Systems III-22
PerkinElmer III-22
Sigma-Aldrich Corp. III-22
Clontech III-23
Waters Corp III-23
Monoclonal and Polyclonal Antibodies Suppliers III-23
Strategic BioSolutions III-23
CALTAG Laboratories III-23
Gallus Immunotech III-24
Maine Biotechnology Services III-24
O.E.M. Concepts, Inc. III-24
Nucleic Acid Extraction Kits Suppliers III-24
Gentra Systems, Inc. III-24
QIAGEN III-24
Biochemistry Reagents and Related Chemical Suppliers III-25
A.G. Scientific, Inc. III-25
Biosource International, Inc. III-25
Kirkegaard & Perry Laboratories III-25
Promega Corporation III-25
Cytokine and Chemokine Testing Reagent and Kits Suppliers III-25
R&D Systems III-25
Cytimmune Science III-26
Cell Culture Suppliers III-26
Advanced Biotechnologies Inc. III-26
Analytical Biological Services Inc III-26
Invitrogen Corp. III-26
JRH Biosciences III-26
Mediatech III-27
Carbohydrate Analysis Reagents Suppliers III-27
Pierce Chemical Co. III-27
Environmental Testing Reagents Suppliers III-27
J.T. Baker III-27
Strategic Diagnostics III-27
B.Market Analytics III-28
Table 44:US Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-28

Table 45:US 10-Year Perspective for Laboratory Chemical
Reagents by Application Area
Percentage Breakdown of
Dollar Sales for Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunohistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets for 2000, 2005 & 2010 (includes corresponding Graph
/Chart) III-29

2. Canada III-30
A.Market Analysis III-30
Biotech Sector Review III-30
Diagnostic Instruments and Reagents III-30
B.Market Analytics III-31
Table 46:Canadian Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-31

Table 47:Canadian 10-Year Perspective for Laboratory
Chemical Reagents by Application Area
Percentage Breakdown
of Dollar Sales for Molecular Biology (Monoclonal &
Polyclonal antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction kits, PCR Reagents,
Enzymes, and Others), Biochemistry (IVD), Cytokine &
Chemokine Testing, Cell Culture, Carbohydrate Analysis,
Immunohistochemistry, and Environmental Testing (Pesticide
Residues and Others) Markets for 2000, 2005 & 2010 (includes
corresponding Graph/Chart) III-32

3. Japan III-33
A.Market Analysis III-33
Research Entities III-33
Reagent Chemicals Market in Japan III-33
Product Launches III-33
Strategic Corporate Developments III-34
Focus on Key Players III-35
Shimadzu Corp. III-35
Takara Biomedical Group III-35
Wako Pure Chemical Industries III-35
B.Market Analytics III-37
Table 48:Japanese Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-37

Table 49:Japanese 10-Year Perspective for Laboratory
Chemical Reagents by Application Area
Percentage Breakdown
of Dollar Sales for Molecular Biology (Monoclonal &
Polyclonal antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction kits, PCR Reagents,
Enzymes, and Others), Biochemistry (IVD), Cytokine &
Chemokine Testing, Cell Culture, Carbohydrate Analysis,
Immunohistochemistry, and Environmental Testing (Pesticide
Residues and Others) Markets for 2000, 2005 & 2010 (includes
corresponding Graph/Chart) III-38

4. Europe III-39
A.Market Analysis III-39
Outlook III-39
Molecular Biology Reagent Market III-39
B.Market Analytics III-40
Table50 :European Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Geographic Region
France,
Germany, United Kingdom, Italy, and Rest of Europe Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2000 through 2010 (includes corresponding
Graph/Chart) III-40

Table 51:European Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-41

Table 52:European 10-Year Perspective for Laboratory
Chemical Reagents by Geographic Region
Percentage
Breakdown of Dollar Sales for France, Germany, United
Kingdom, Italy, and Rest of Europe Markets for Years 2000,
2005 & 2010 (includes corresponding Graph/Chart) III-42

Table 53:European 10-Year Perspective for Laboratory
Chemical Reagents by Application Area
Percentage Breakdown
of Dollar Sales for Molecular Biology (Monoclonal &
Polyclonal antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction kits, PCR Reagents,
Enzymes, and Others), Biochemistry (IVD), Cytokine &
Chemokine Testing, Cell Culture, Carbohydrate Analysis,
Immunohistochemistry, and Environmental Testing (Pesticide
Residues and Others) Markets for 2000, 2005 & 2010 (includes
corresponding Graph/Chart) III-43

4a. France III-44
A.Market Analysis III-44
Product Launches/ Innovations III-44
Strategic Corporate Developments
Historic III-44
Key Player III-45
Biomerieux III-45
B.Market Analytics III-46
Table 54:French Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-46

Table 55:French 10-Year Perspective for Laboratory Chemical
Reagents by Application Area
Percentage Breakdown of
Dollar Sales for Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunohistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets for 2000, 2005 & 2010 (includes corresponding
Graph/Chart) III-47

4b. Germany III-48
A.Market Analysis III-48
Research Entities III-48
Analytical Instruments and Supplies Market III-48
Strategic Corporate Developments III-49
Key Player III-50
Merck KgaA III-50
B.Market Analytics III-51
Table 56:German Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-51

Table 57:German 10-Year Perspective for Laboratory Chemical
Reagents by Application Area
Percentage Breakdown of
Dollar Sales for Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunohistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets for 2000, 2005 & 2010 (includes corresponding Graph
/Chart) III-52

4c. United Kingdom III-53
A.Market Analysis III-53
Biotechnology Industry III-53
Strategic Corporate Developments III-53
Key Players III-54
B.Market Analytics III-55
Table 58:UK Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-55

Table 59:UK 10-Year Perspective for Laboratory Chemical
Reagents by Application Area
Percentage Breakdown of
Dollar Sales for Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunohistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets for 2000, 2005 & 2010 (includes corresponding Graph
/Chart) III-56

4d. Italy III-57
A.Market Analysis III-57
Biotech Sector Review III-57
B.Market Analytics III-58
Table 60:Italian Recent Past, Current & Future Analysis for
Laboratory Chemical Reagents by Application Area
Molecular
Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-58

Table 61:Italian 10-Year Perspective for Laboratory Chemical
Reagents by Application Area
Percentage Breakdown of
Dollar Sales for Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunohistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets for 2000, 2005 & 2010 (includes corresponding Graph
/Chart) III-59

4e. Rest of Europe III-60
A.Market Analysis III-60
Spain- A Promising IVD Market III-60
Scandinavia
An Important Biotech Market III-60
Sweden III-60
Switzerland III-61
Focus on Players and Suppliers III-61
Lonza Biologics (Switzerland) III-61
Strategic Corporate Developments III-61
B.Market Analytics III-63
Table 62:Rest of Europe Recent Past, Current & Future
Analysis for Laboratory Chemical Reagents by Application
Area
Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunhistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-63

Table 63:Rest of Europe 10-Year Perspective for Laboratory
Chemical Reagents by Application Area
Percentage Breakdown
of Dollar Sales for Molecular Biology (Monoclonal &
Polyclonal antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction kits, PCR Reagents,
Enzymes, and Others), Biochemistry (IVD), Cytokine &
Chemokine Testing, Cell Culture, Carbohydrate Analysis,
Immunohistochemistry, and Environmental Testing (Pesticide
Residues and Others) Markets for 2000, 2005 & 2010 (includes
corresponding Graph/Chart) III-64

5. Asia-Pacific III-65
A.Market Analysis III-65
Select Market Review III-65
Australia and New Zealand III-65
In Vitro Diagnostics Market III-65
Biotech Sector III-65
China III-65
In Vitro Diagnostics Market III-66
India III-66
IVD Market III-66
Expanding Biotech Sector III-66
End-Use Market III-66
Taiwan III-66
Strategic Corporate Developments III-67
B.Market Analytics III-68
Table 64:Asia-Pacific Recent Past, Current & Future Analysis
for Laboratory Chemical Reagents by Application Area -
Molecular Biology (Monoclonal & Polyclonal antibodies, Gene
Expression, Vectors, Cloning, & Sequencing, Gene Synthesis,
Extraction kits, PCR Reagents, Enzymes, and Others),
Biochemistry (IVD), Cytokine & Chemokine Testing, Cell
Culture, Carbohydrate Analysis, Immunhistochemistry, and
Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-68

Table 65:Asia-Pacific 10-Year Perspective for Laboratory
Chemical Reagents by Application Area
Percentage Breakdown
of Dollar Sales for Molecular Biology (Monoclonal &
Polyclonal antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction kits, PCR Reagents,
Enzymes, and Others), Biochemistry (IVD), Cytokine &
Chemokine Testing, Cell Culture, Carbohydrate Analysis,
Immunohistochemistry, and Environmental Testing (Pesticide
Residues and Others) Markets for 2000, 2005 & 2010 (includes
corresponding Graph/Chart) III-69

6. Latin America III-70
A.Market Analysis III-70
Analytical Instruments and Supplies Market III-70
B.Market Analytics III-71
Table 66:Latin American Recent Past, Current & Future
Analysis for Laboratory Chemical Reagents by Application
Area
Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunhistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-71

Table 67:Latin American 10-Year Perspective for Laboratory
Chemical Reagents by Application Area
Percentage Breakdown
of Dollar Sales for Molecular Biology (Monoclonal &
Polyclonal antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction kits, PCR Reagents,
Enzymes, and Others), Biochemistry (IVD), Cytokine &
Chemokine Testing, Cell Culture, Carbohydrate Analysis,
Immunohistochemistry, and Environmental Testing (Pesticide
Residues and Others) Markets for 2000, 2005 & 2010 (includes
corresponding Graph/Chart) III-72

7. Rest of World III-73
A.Market Analysis III-73
Middle East III-73
B.Market Analytics III-74
Table 68:Rest of World Recent Past, Current & Future
Analysis for Laboratory Chemical Reagents by Application
Area
Molecular Biology (Monoclonal & Polyclonal
antibodies, Gene Expression, Vectors, Cloning, & Sequencing,
Gene Synthesis, Extraction kits, PCR Reagents, Enzymes, and
Others), Biochemistry (IVD), Cytokine & Chemokine Testing,
Cell Culture, Carbohydrate Analysis, Immunhistochemistry,
and Environmental Testing (Pesticide Residues and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-74

Table 69:Rest of World 10-Year Perspective for Laboratory
Chemical Reagents by Application Area
Percentage Breakdown
of Dollar Sales for Molecular Biology (Monoclonal &
Polyclonal antibodies, Gene Expression, Vectors, Cloning, &
Sequencing, Gene Synthesis, Extraction kits, PCR Reagents,
Enzymes, and Others), Biochemistry (IVD), Cytokine &
Chemokine Testing, Cell Culture, Carbohydrate Analysis,
Immunohistochemistry, and Environmental Testing (Pesticide
Residues and Others) Markets for 2000, 2005 & 2010 (includes
corresponding Graph/Chart) III-75


IV. COMPETITION

1. A.G. Scientific, Inc. (USA) IV-1
2. Abbott Laboratories (USA) IV-5
Table 70: Half Yearly Sales Analysis: 2004-2005 (H1)
(In US$ million) IV-7

Table 71: Half Yearly Sales Analysis by Segment: 2004-
2005 (H1) (In US$ million) IV-8

Table 72: Quarterly Sales Analysis: 2003-2004 (In US$
million) IV-8

Table 73: Annual Sales Analysis by Segment: 2003-2004
(In US$ million) IV-8

Table 74: Annual Sales Analysis by Geographical Region:
2003-2004 (In US$ million) IV-8
Abbott Diagnostics (USA) IV-24
3. Abcell OY Corporation (Finland) IV-27
4. Abgene (UK) IV-29
5. ABR--Affinity BioReagents, Inc. (USA) IV-31
6. Advanced Biotechnologies, Inc. (USA) IV-32
7. Advanced ChemTech, Inc. (USA) IV-35
8. Advanced Technology and Industrial Co., Ltd. (Hong Kong) IV-36
9. AES Laboratories (France) IV-37
10. Agilent Technologies, Inc. (USA) IV-39
Table 75: First Quarter Sales Analysis: 2004-2005 (Q1)
(In US$ million) IV-41

Table 76: First Quarter Sales Analysis by Segment:
2004-2005 (Q1) (In US$ million) IV-41
Table 77: First Quarter Sales Analysis by Geographical
Region: 2004-2005 (Q1) (In US$ million) IV-41
Table 78: Annual Sales Analysis: 2003-2004 (In US$
million) IV-41

Table 79: Quarterly Sales Analysis: 2003-2004 (In US$
million) IV-42

Table 80: Annual Sales Analysis by Segment: 2003-2004
(In US$ million) IV-42

Table 81: Annual Sales Analysis by Geographical Region:
2003-2004 (In US$ million) IV-42
11. Alltech Associates, Inc. (USA) IV-51
12. Alpha Diagnostic International, Inc. (USA) IV-54
13. Alpha Innotech Corporation (USA) IV-57
14. Ambion, Inc. (USA) IV-59
15. American Bioanalytical, Inc. (USA) IV-64
16. American Type Culture Collection (USA) IV-66
17. Amresco, Inc. (USA) IV-68
18. Analis SA NV (Belgium) IV-70
19. Analytical Biological Services, Inc. (USA) IV-71
20. Analytical Products Group, Inc. (USA) IV-71
21. Antigenix America, Inc. (USA) IV-72
22. Applera Corp. (USA) IV-74
Table 82: Nine Months Sales Analysis: 2004-2005 (Nine
Months Ended, March) (In US$ million) IV-75

Table 83: Annual Sales Analysis: 2003-2004 (In US$
million) IV-76

Table 84: Annual Sales Analysis by Quarter: 2003-2004
(In US$ million) IV-76

Table 85: Annual Sales Analysis by Segment: 2003-2004
(In US$ million) IV-76

Table 86: Annual Sales Analysis by Geographical Region:
2003-2004 (In US$ million) IV-76
PerkinElmer Life And Analytical Sciences, Inc. (USA) IV-85
Applied Biosystems Group (USA) IV-87
23. Argene SA (France) IV-90
Argene, Inc. (USA) IV-92
24. Asahi Glass Co., Ltd. (Japan) IV-94
Table 87: Half Yearly Sales Analysis: 2004-2005 (H1)
(In Ґ billion) IV-96

Table 88: Half Yearly Sales Analysis by Segment: 2004-
2005 (H1) (In Ґ billion) IV-96
Table 89: Half Yearly Sales Analysis by Geographical
Region: 2004-2005 (H1) (In Ґ billion) IV-96
Table 90: Annual Sales Analysis: 2003-2004 (In Ґ
billion) IV-96

Table 91: Annual Sales Analysis by Segment: 2003-2004
(In Ґ billion) IV-97

Table 92: Annual Sales Analysis by Geographical Region:
2003-2004 (In Ґ billion) IV-97
25. ATG Laboratories, Inc. (USA) IV-103
26. Autogen Bioclear UK Ltd. (UK) IV-105
27. Avanti Polar Lipids, Inc. (USA) IV-105
28. Bachem Bioscience, Inc. (USA) IV-106
29. Bayer Diagnostics (USA) IV-107
Bayer HealthCare -Diagnostic Div (Canada) IV-110
30. Bayou Biolabs (USA) IV-111
31. Beckman Coulter, Inc. (USA) IV-112
Table 93: First Quarter Sales Analysis: 2004-2005 (Q1)
(In US$ million) IV-115

Table 94: First Quarter Sales Analysis by Segment:
2004-2005 (Q1) (In US$ million) IV-115
Table 95: First Quarter Sales Analysis by Geographical
Region: 2004-2005 (Q1) (In US$ million) IV-115
Table 96: Annual Sales Analysis: 2003-2004 (In US$
million) IV-115

Table 97: Annual Sales Analysis by Segment: 2003-2004
(In US$ million) IV-115

Table 98: Annual Sales Analysis by Geographical Region:
2003-2004 (In US$ million) IV-116
32. Becton, Dickinson & Company (USA) IV-125
Table 99: Half-Yearly Sales Analysis: 2004-2005 (H1)
(In US$ million) IV-127

Table 100: Half-Yearly Sales Analysis by Segment: 2004
-2005 (H1) (In US$ million) IV-127

Table 101: Annual Sales Analysis: 2003-2004 (In US$
million) IV-127
BD Biosciences (USA) IV-140
BD Biosciences Clontech (USA) IV-141
BD Biosciences Pharmingen (USA) IV-144
BD Immunocytometry Systems (USA) IV-145
33. Bel Art Products (USA) IV-148
34. Biacore International AB (Sweden) IV-149
35. Bioanalytical Systems, Inc. (USA) IV-153
36. Biochemical Diagnostics, Inc. (USA) IV-155
37. Bioclone Australia Pty., Limited (Australia) IV-155
38. Bioclonetics, Inc. (USA) IV-156
39. Biodesign International (USA) IV-157
40. BioGenex Laboratories, Inc. (USA) IV-158
41. Biokit SA (Spain) IV-165
42. Biological Research Faculty & Facility, Inc. (USA) IV-173
43. BIOLOGOS, INC. IV-175
44. BioMed Labs (UK) IV-176
45. Biomeda Corporation (USA) IV-178
46. Biomedical Technologies, Inc. (USA) IV-184
47. Biomйrieux SA (France) IV-186
Table 102: Half Yearly Sales Analysis: 2004-2005 (H1)
(In Ђ million) IV-186

Table 103: Annual Sales Analysis: 2003-2004 (In Ђ
million) IV-186
48. Biomol Research Laboratories, Inc. (USA) IV-188
Biomol GmbH (Germany) IV-190
49. Bioquest Limited (Australia) IV-195
50. Bio-Rad Laboratories, Inc. (USA) IV-196
Table 104: Half Yearly Sales Analysis: 2004-2005 (H1)
(In US$ billion) IV-197

Table 105: Annual Sales Analysis: 2003-2004 (In US$
billion) IV-197

Table 106: Annual Sales Analysis by Segment: 2003-2004
(In US$ billion) IV-198

Table 107: Annual Sales Analysis by Geographical
Region: 2003-2004 (In US$ billion) IV-198

Table 108: Quarterly Sales Analysis: 2003-2004 (In US$
billion) IV-198
Bio-Rad Laboratories Ltd. (Canada) IV-207
Bio-Rad Life Science Group (USA) IV-207
51. Bioreclamation, Inc. (USA) IV-208
52. Bioresearch Ireland (Ireland) IV-211
53. Biosource International, Inc. (USA) IV-212
54. Biosynth AG (Switzerland) IV-217
55. Biotecx Laboratories, Inc. (USA) IV-218
56. Biotest AG (Germany) IV-220
Table 109: First Quarter Sales Analysis: 2004-2005 (Q1)
(In Ђ million) IV-220

Table 110: First Quarter Sales Analysis by Segment:
2004-2005 (Q1) (In Ђ million) IV-220

Table 111: Annual Sales Analysis: 2002-2004 (In Ђ
million) IV-221
57. Biotools B&M Labs SA (Spain) IV-223
58. Blue Heron Biotechnology, Inc. (USA) IV-225
59. Boehringer Ingelheim GmbH (Germany) IV-226
Table 112: Annual Sales Analysis: 2003-2004 (In Ђ
million) IV-226

Table 113: Annual Sales Analysis by Product Segment:
2003-2004 (In Ђ million) IV-226

Table 114: Annual Sales Analysis by Region: 2003-2004
(In Ђ million) IV-227
60. Boston Biochem, Inc. (USA) IV-232
61. BT&C, Inc. (USA) IV-234
62. Caltag Laboratories, Inc. (USA) IV-237
63. Cambrex Corporation (USA) IV-238
64. Carl Roth GmbH & Co. (Germany) IV-241
65. Carlo Erba Reagenti (Italy) IV-242
66. Cascade Biologics, Inc., (USA) IV-244
67. CBS Scientific Company, Inc. (USA) IV-245
68. Cell And Molecular Technologies, Inc. (USA) IV-246
69. Cell Sciences, Inc. (USA) IV-247
70. Cellabs Pty. Ltd. (Australia) IV-249
71. Centerchem, Inc. (USA) IV-251
72. Chromagen, Inc. (USA) IV-253
73. Chromsystems Instruments & Chemicals GmbH (Germany) IV-255
74. Clin-Tech Ltd. (UK) IV-257
75. Cortex Biochem, Inc. (USA) IV-258
76. Crescent Chemicals Company, Inc. (USA) IV-261
77. CSL Limited (Australia) IV-262
JRH Biosciences, Inc. (USA) IV-267
78. Cytimmune Science, Inc. (USA) IV-269
79. Dade Behring, Inc. (USA) IV-271
80. Dako Cytomation Denmark A/S (Denmark) IV-276
81. DCS Innovative Diagnostik Systeme (Germany) IV-278
82. Diacron, Srl (Italy) IV-279
83. Diagnostic BioSystems (USA) IV-280
84. DiaSorin, SpA (Italy) IV-283
Diasorin, Inc. (USA) IV-284
85. Diatech, SRL (Italy). IV-286
86. Dionex Corporation (USA) IV-287
87. DNA Technology A/S (Denmark) IV-289
88. Dr. Bruno Lange GmbH & Co. KG (Germany) IV-291
89. East Coast Biologics, Inc. (USA) IV-293
90. Enzon Pharmaceuticals, Inc. (USA) IV-295
91. Enzyme Systems Products, Inc. (USA) IV-297
92. Epicentre Technologies Corporation (USA) IV-298
93. Eppendorf-5 Prime, Inc. (USA) IV-300
94. ESA, Inc. (USA) IV-301
95. Euro-Diagnostica AB (Sweden) IV-303
96. Eurogenetics Italy SRL (Italy) IV-304
97. Exalpha Biologicals, Inc. (USA) IV-305
98. Fermentas, Inc. (USA) IV-306
99. Fisher Scientific International, Inc. (USA) IV-307
Perbio Science AB (Sweden) IV-309
100. Fitzgerald Industries International, Inc. (USA) IV-311
101. Flownamics Analytical Instruments, Inc. (USA) IV-312
102. Fotodyne, Inc. (USA) IV-314
103. Gala Design, Inc. (USA) IV-316
104. Gallus Immunotech, Inc . (Canada) IV-317
105. Gamma SA (Belgium) IV-318
106. Genaxis Biotechnology (France) IV-319
107. GenHunter Corporation (USA) IV-320
108. Geno Technology, Inc. (USA) IV-323
109. Genomic Solutions, Inc. (USA) IV-325
110. Gentra Systems, Inc. (US) IV-329
111. GERBU Biochemicals GmbH (Germany) IV-331
112. Glen Research Corporation (USA) IV-333
113. Glyko, Inc. (USA) IV-334
114. Gradipore Limited (Australia) IV-335
115. Green Mountain Antibodies (USA) IV-337
116. GroPep Limited (Australia) IV-338
117. Harlan Bioproducts For Science, Inc. (USA) IV-340
118. Helena Laboratories, Inc. (USA) IV-341
Helena BioSciences (UK) IV-344
119. HyTest Ltd. (Finland) IV-348
120. Imgenex Corporation (USA) IV-350
121. Immucor, Inc. (USA) IV-356
122. Immuno-Mycologics, Inc. (USA) IV-358
123. In Vivo Scribe Technologies, LLC. (USA) IV-360
124. Inamco International Corporation (USA) IV-361
125. Incell Corporation, LLC. (USA) IV-362
126. Incyte Corporation (USA) IV-364
127. International Immunology Corporation (USA) IV-367
128. Intracel Corporation (USA) IV-368
129. Invitrogen Corporation (USA) IV-369
130. Irvine Scientific, Inc. (USA) IV-372
131. J.T Baker, Inc. (USA) IV-375
132. Jackson ImmunoResearch Laboratories, Inc. (USA) IV-378
133. Kamiya Biomedical Company (USA) IV-381
134. KD Medical, Inc. (USA) IV-382
135. Kem-En-Tec A/S (Denmark) IV-383
136. Kent Labs, Inc. (USA) IV-385
137. Kirkegaard & Perry Laboratories, Inc. (USA) IV-386
138. Linco Research, Inc. (USA) IV-387
139. Lonza Biologics, Inc. (USA) IV-389
140. Maine Biotechnology Services, Inc. (USA) IV-390
141. Marin Biologic Laboratories (USA) IV-391
142. Marker Gene Technologies, Inc. (USA) IV-396
143. Mediatech, Inc. (USA) IV-398
144. Medipac Scientific Pty., Ltd. (Australia) IV-400
145. Medix Biochemica OY AB (Finalnd) IV-402
146. Merck KGaA (Germany) IV-408
EMD Biosciences, Inc. (USA) IV-411
EMD Chemicals, Inc. (USA) IV-417
147. Meridian Bioscience, Inc. (USA) IV-419
148. Microzone Limited (UK) IV-420
149. Midland Bioproducts Corporation (MBC) (USA) IV-423
150. Miltenyi Biotec GmbH (Germany) IV-424
151. Mobitec GmbH (Germany) IV-428
152. Molecular Biosciences, Inc. (USA) IV-431
153. Molecular Devices Corporation (USA) IV-432
154. Molecular Research Center, Inc. (USA) IV-440
155. MP Biomedicals, Inc. (USA) IV-444
156. Neogen Corporation (USA) IV-446
157. New England Biolabs, Inc. (USA) IV-455
158. Nordic Immunological Laboratories (The Netherlands) IV-457
159. Norgen Biotek Corporation (Canada) IV-458
160. Novocastra Laboratories, Ltd. (UK) IV-459
161. Novozymes Biotech, Inc. (USA) IV-460
162. OEM Concepts, Inc. (USA) IV-461
163. Olympus France SA (France) IV-463
164. Operon, SA (Spain) IV-465
165. Ortho-Clinical Diagnostics, Inc. (USA) IV-467
166. Owl Separations Systems (USA) IV-470
167. Owl Separation Systems (USA) IV-471
168. Oxford Biomedical Research, Inc. (USA) IV-473
169. Oxoid Australia Pty Ltd. (Australia) IV-477
170. PanBio Pty., Ltd. (Australia) IV-481
171. Panreac Quimica SA (Spain) IV-483
172. Perkinelmer, Inc. (USA) IV-485
Table 115: Half Yearly Sales Analysis: 2004-2005 (H1)
(In US$ million) IV-486

Table 116: Half Yearly Sales Analysis by Business
Segment: 2004-2005 (H1) (In US$ million) IV-487

Table 117: Annual Sales Analysis: 2003-2004 (In US$
million) IV-487

Table 118: Annual Sales Analysis by Business Segment:
2003-2004 (In US$ million) IV-487

Table 119: Annual Sales Analysis by Geographical
Region: 2003-2004 (In US$ million) IV-487
173. PerkinElmer Life And Analytical Sciences, Inc. (USA) IV-490
174. Peprotech, Inc. (USA) IV-492
175. Pierce Biotechnology, Inc. (USA) IV-494
176. Prime Synthesis, Inc. (USA) IV-495
177. Progen Industries Ltd. (Australia) IV-497
178. Prokaria (Iceland) IV-498
179. Promega Corporation (USA) IV-499
Romega UK Limited (UK) IV-501
180. Protedyne (USA) IV-505
181. Protos Immunoresearch (USA) IV-511
182. Psiron Ltd. (Australia) IV-512
183. Qbiogene, Inc. (USA) IV-514
184. QED Bioscience, Inc. (USA) IV-516
185. Qiagen N.V (The Netherlands) IV-518
Qiagen, Inc. (USA) IV-522
186. Quartett Immunodiagnostika und Biotechnologie Vertriebs
GmbH (Germany) IV-524
187. R&D Systems, Inc. (USA) IV-525
188. Reagecon Diagnostics Ltd. (Ireland) IV-527
189. Reagena Oy Ltd. (Finland) IV-529
190. Reagents, Inc. (USA) IV-530
191. Regis Technologies, Inc. (USA) IV-531
192. Repligen, Corp. (USA) IV-532
193. Research Organics, Inc. (USA) IV-534
194. Retrogen, Inc. (USA) IV-536
195. Roche Diagnostics Corporation (USA) IV-538
Roche Applied Science (USA) IV-538
Roche Diagnostics (Deutschland) GmbH (Germany) IV-541
Roche Diagnostics (Switzerland) AG (Switzerland) IV-541
Roche Diagnostics Australia Pty Limited (Australia) IV-542
Roche Diagnostics Nederland BV (The Netherlands) IV-542
196. Rockland Immunochemicals, Inc. (USA) IV-543
197. Sangtec Molecular Diagnostics (Sweden) IV-548
198. Santa Cruz Biotechnology, Inc. (USA) IV-551
199. Scytek Laboratories, Inc. (USA) IV-552
200. Serologicals Corporation (USA) IV-557
Chemicon International, Inc. (USA) IV-562
Chemicon Australia Pty. Ltd. (Australia) IV-565
201. Severn Biotech Limited (UK) IV-566
202. Shimadzu Corporation (Japan) IV-568
Shimadzu Scientific Instruments, Inc. (USA) IV-573
203. Sigma-Aldrich Corporation (USA) IV-579
Sigma-Genosys (USA) IV-582
204. Southern Biotechnology Associated, Inc. (USA) IV-583
205. Spectral Diagnostics, Inc. (Canada) IV-584
206. Stratagene, Inc. (USA) IV-585
207. Strategic Diagnostics, Inc. (USA) IV-594
Strategic Biosolutions (USA) IV-595
208. Synthelec AB (Sweden) IV-596
209. Sysmex Singapore Pte., Ltd. (Singapore) IV-596
210. Takara Biomedical Group (Japan) IV-596
211. Talent S.R.L. (Italy) IV-597
212. Tecra International Pty., Ltd. (Australia) IV-599
213. Tepnel Lifecodes Corporation (USA) IV-603
214. The Binding Site Ltd. (UK) IV-605
215. Thermo Electron Corporation (USA) IV-607
Thermo Trace, Ltd. (Australia) IV-612
216. TNB Laboratories, Inc. (Canada) IV-613
217. Transgenomic, Inc. (USA) IV-614
218. Trevigen, Inc. (USA) IV-617
219. United States Biological (USA) IV-622
220. UpFront Chromatography A/S (Denmark) IV-624
221. Upstate Biotechnology (USA) IV-626
222. Vector Laboratories, Inc. (USA) IV-629
223. Ventana Medical Systems, Inc. (USA) IV-632
224. Viragen, Inc. (USA) IV-636
225. Virostat, Inc. (USA) IV-638
226. Wako Pure Chemical Industries, Ltd. (Japan) IV-639
Wako Chemicals USA, Inc. (USA) IV-639
227. Waters Corporation (USA) IV-643
228. Worthington Biochemical Corporation (USA) IV-645
229. Yamasa Corporation (Japan) IV-648
230. Zeptometrix Corporation (USA) IV-649




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